PHARMACOKINETICS OF FLUMAZENIL AND MIDAZOLAM
نویسندگان
چکیده
منابع مشابه
Effect of flumazenil on midazolam-induced amnesia.
We have studied the effect of i.v. flumazenil 0.01 mg kg-1 on the amnesia and sedation caused by midazolam 2 mg and 5 mg i.v. in volunteers in order to determine the relationship between the actions of the antagonist on these two effects. Midazolam caused dose-dependent central neural depression as assessed by critical flicker fusion frequency, and dose-dependent amnesia for word cards. In subj...
متن کاملMidazolam sedation reversed with flumazenil for cardioversion.
Midazolam was used for anaesthesia in 20 patients undergoing cardioversion; 10 received flumazenil, which caused immediate rapid reversal of anaesthesia, and these patients maintained SpO2 greater than 95%, breathing air, within 5-10 min. In contrast, patients in the placebo group were still partially sedated and required oxygen therapy for up to 2 h to maintain a normal SpO2. Arterial pressure...
متن کاملThe use of midazolam and flumazenil for invasive radiographic procedures.
This study has examined the use of flumazenil to improve recovery following sedation with midazolam in elderly patients undergoing invasive radiological procedures. Forty patients received either flumazenil or placebo in a randomized double-blind fashion following midazolam sedation. Nalbuphine 10-15 mg was given for premedication. All but one of the patients in the flumazenil group were fully ...
متن کاملAcute dystonia induced by midazolam and abolished by flumazenil
inhibitor enoximone.' We describe a case of tonic-clonic convulsions associated with intravenous administration of enoximone, a possible adverse effect that has hitherto not been reported. A 66 year old white man was admitted with a large anteroseptal myocardial infarction due to occlusion of the left anterior descending coronary artery. He developed a ventricular septal defect within 48 hours ...
متن کاملAcute dystonia induced by midazolam and abolished by flumazenil
inhibitor enoximone.' We describe a case of tonic-clonic convulsions associated with intravenous administration of enoximone, a possible adverse effect that has hitherto not been reported. A 66 year old white man was admitted with a large anteroseptal myocardial infarction due to occlusion of the left anterior descending coronary artery. He developed a ventricular septal defect within 48 hours ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1993
ISSN: 0007-0912
DOI: 10.1093/bja/70.3.286